solvent-free multicomponent reactions of dithiocarbamates, activated acetylenes and isocyanides

Solvent-Free Multicomponent Reactions of Dithiocarbamates, Activated Acetylenes and Isocyanides

An efficient method to synthesis the 2H-pyrans using three component reactions of dithiocarbamats, activated acetylenes and isocyanides in water as the solvent is described. In these reactions, synthesis of 2H-pyrans is possible based on the one-pot reaction and without using any catalyst. The mild reaction conditions and high yields of the products exhibit synthetic advantage of these methods.

SOLVENT-FREE SYNTHESIS OF PYRROL DERIVATIVES USING MULTICOMPONENT REACTIONS OF 1,3-‎DICARBONYLS, ACTIVATED CARBONYL COMPOUNDS, AND PRIMARY ALKYLAMINES

one-pot synthesis of pyrrole derivatives via reaction between activated carbonyl compounds, primary amines and 1,3-dicarbonyls under solvent-free conditions is described‎.

SOLVENT-FREE SYNTHESIS OF PYRROL DERIVATIVES USING MULTICOMPONENT REACTIONS OF 1,3-‎DICARBONYLS, ACTIVATED CARBONYL COMPOUNDS, AND PRIMARY ALKYLAMINES

A one-pot synthesis of pyrrole derivatives via reaction between activated carbonyl compounds, primary amines and 1,3-dicarbonyls under solvent-free conditions is described‎.

Chemistry of the isocyanides and their multicomponent reactions , including their libraries – the initiatives of Ivar Ugi

Multicomponent Solvent-Free Synthesis, Antimicrobial and Antifungal Evaluation of Novel N-Amino Benzylthiolates

Novel N-amino benzylthiolates were synthesized via multicomponent reaction of malononitrile, isothiocyanates and benzyl halides under conventional and solvent-free conditions. Various electron-donating and -withdrawing substitutes within both isothiocyanates and benzyl halides were used to demonstrate the efficiency of new methodology. A broad spectrum of antibacterial and antifungal activities...

Application of H2O as the Green Solvent for the Synthesis of Phosphonates via Multicomponent Reactions

Phosphonate derivatives were prepared using multicomponent reactions of dialkyl acetylenedicarboxylate with 4-hydroxycumarine in the presence of trimethyl or triphenyl phosphite in good yields.